Comparison of intraoperative administration of ketorolac with morphine in pain control and postoperative nausea and vomiting in patients undergoing rhinoplasty

Comparison of intraoperative administration of ketorolac with morphine in pain control and postoperative nausea and vomiting in patients undergoing rhinoplasty in Jahrom in 2022

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210415050976N8

Enrollment

114

Registered

2021-10-20

Start date

2021-11-01

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhinoplasty surgery. General- and plastic-surgery devices associated with adverse incidents

Interventions

Intervention 1: Intervention group 1: 0.5 mg / kg morphine will be injected intravenously after induction of anesthesia. Intervention 2: Intervention group 2: 30 mg ketorolac (ampoule) will be injecte

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Rhinoplasty under general anesthesia No history of allergy to morphine and ketorolac

Exclusion criteria

Exclusion criteria: Drug addiction Underlying cardiovascular disease Patients with coagulation disorders or platelets less than one hundred thousand Patients with a history of renal insufficiency and serum creatinine more than one and a half

Design outcomes

Primary

Measure	Time frame
The pain. Timepoint: Periods immediately after surgery, 15 minutes, 3 hours and 6 hours after surgery. Method of measurement: VAS criteria.;Nausea and vomiting. Timepoint: After surgery. Method of measurement: Nausea and vomiting questionnaire.	—

Secondary

Measure	Time frame
Vital signs. Timepoint: Immediately after surgery and then at 15, 3 and 6 minutes after surgery. Method of measurement: monitoring.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNavid Kalani

Jahrom University of Medical Sciences

k.navid@jums.ac.ir+98 71 2536 5231

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026