Postoperative Sore Throat in General Anesthesia Using Laryngeal Mask Airway versus Endotracheal Tube After Administration of Topical and Intravenous Lidocaine

Comparison of the Incidence of Postoperative Sore Throat in Patients Undergoing General Anesthesia with Laryngeal Mask Airway and endotracheal tube Using Saline, Lidocaine Gel, Lidocaine Bolus, and Lidocaine Infusion in Upper Limb Orthopedic Surgeries

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210415050976N18

Enrollment

240

Registered

2026-04-17

Start date

2026-05-31

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sore Throat.

Interventions

Intervention 1: Control Group 1: For airway management in this group, a laryngeal mask airway (LMA) was used. A total of 2 cc of normal saline was drawn up and separately poured onto the cuff of the t

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Elective patients undergoing upper limb orthopedic surgery under general anesthesia Surgery lasting less than 2 hours providing informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Severe asthma history Active upper respiratory tract infection at the time of surgery History of difficult airway management, Patients with severe systemic diseases such as advanced heart or renal failure Pregnancy or lactation Coagulation disorders or use of anticoagulant medications Known hypersensitivity to lidocaine or other local anesthetics Use of antiarrhythmic drugs that interact with lidocaine (e.g., amiodarone) Active airway bleeding.

Design outcomes

Primary

Measure	Time frame
Sore Throat. Timepoint: In the first 24 hours and 14 days after intervention. Method of measurement: A four-point checklist for pain intensity will be used.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNavid Kalani

Jahrom University of Medical Sciences

k.navid@jums.ac.ir+98 71 5434 4002

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026