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Comparison of four drugs clonidine, bisoprolol, tranexamic acid and gabapentin on bleeding rate, hemodynamic stability and intraoperative surgeon satisfaction in patients undergoing rhinoplasty surgery.

Comparison of four drugs clonidine, bisoprolol, tranexamic acid and gabapentin on bleeding rate, hemodynamic stability and intraoperative surgeon satisfaction in patients undergoing rhinoplasty surgery.

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210415050976N11
Enrollment
130
Registered
2022-05-05
Start date
2022-05-10
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhinoplasty surgery. Rhinoplasty surgery

Interventions

Intervention 1: Intervention group 1: They will receive clonidine 0/2 mg intravenously. Intervention 2: Intervention group 2: They will receive 5.2 mg bisoprolol tablets. Intervention 3: Intervention

Sponsors

Jahrom University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Hemoglobin above 10 Lack of sensitivity to the drugs used

Exclusion criteria

Exclusion criteria: Patients with coagulation disorders Blood pressure Coronary artery disease

Design outcomes

Primary

MeasureTime frame
Blood preasure. Timepoint: Before induction? after induction? 1 minute after induction?5 minutes after induction? 30? 60? 90 and 120 minutes during operation? enter recovery and exit recovery. Method of measurement: Monitoring.;Surgeon Satisfaction. Timepoint: During the operation every 15 minutes after the start of surgery and at the end of the operation. Method of measurement: Beozaart Scale.;Bleeding. Timepoint: During the operation. Method of measurement: The amount of bleeding in the suction in milliliters.

Secondary

MeasureTime frame
Relaxation. Timepoint: In recovery. Method of measurement: Ramsey sedation criteria.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNavid Kalani

Jahrom University of Medical Sciences

k.navid@jums.ac.ir+98 71 2536 5231

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026