Comparison of the effect of adding pethidine to half-percent bupivacaine and half-percent ropivacaine on pain intensity in women undergoing elective cesarean section

Comparison of the effect of adding pethidine to bupivacaine and half of ropivacaine on the severity of pain in women referred to Motahari Hospital during elective cesarean section.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210415050976N10

Enrollment

Registered

2022-02-19

Start date

2021-11-01

Completion date

Unknown

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean section. Onset (spontaneous) of labor after 37 completed weeks of gestation but before 39 completed weeks gestation, with delivery by (planned) cesarean section

Interventions

Intervention 1: Intervention group: 12/5mg of bupivacaine as a local anesthetic made by Abu Reihan Pharmaceutical Company + 10 mg of pethidine as a narcotic made by Elixir Pharmaceutical Company Recei

Eligibility

Sex/Gender

Female

Age

17 Years to 45 Years

Inclusion criteria

Inclusion criteria: Hemodynamic stability Not having infection at the site of needle entry Not having High intracranial pressure Not having coagulation disorders

Exclusion criteria

Exclusion criteria: History of addiction Allergy to drugs Obesity

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: When entering the operating room, when entering the recovery, leaving the recovery, 2 hours after the operation, 6 hours after the operation, 12 hours after the operation and 24 hours after the operation. Method of measurement: Visual scale of pain.	—

Secondary

Measure	Time frame
Blood pressure changes. Timepoint: Before the operation, before the spinal, immediately after the spinal, after the baby is born and then every 10 minutes until the end of the operation, when entering the recovery, when leaving the recovery). Method of measurement: monitoring.;Heart Rate. Timepoint: Before the operation, before the spinal, immediately after the spinal, after the baby is born and then every 10 minutes until the end of the operation, when entering the recovery, when leaving the recovery). Method of measurement: monitoring.	—

Measure

Time frame

Blood pressure changes. Timepoint: Before the operation, before the spinal, immediately after the spinal, after the baby is born and then every 10 minutes until the end of the operation, when entering the recovery, when leaving the recovery). Method of measurement: monitoring.;Heart Rate. Timepoint: Before the operation, before the spinal, immediately after the spinal, after the baby is born and then every 10 minutes until the end of the operation, when entering the recovery, when leaving the recovery). Method of measurement: monitoring.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNavid Kalani

Jahrom University of Medical Sciences

k.navid@jums.ac.ir+98 71 2536 5231

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026