Patients with traumatic brain injury. Traumatic cerebral edema with loss of consciousness of any duration with death due to brain injury prior to regaining consciousness
Conditions
Interventions
Intervention 1: Intervention group 1: Patients in group 1 will receive sodium thiopental drug in the intensive care unit as a bolus of 2 mg per kg of body weight and a maintenance dose of 2 to 6 mg pe
Sponsors
Jahrom University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Satisfaction to participate in the study Consciousness level less than 8 according to Glasgow Coma Scale (GCS) Head injury without damage to other vital organs Full consent of the patient and his / her legal guardians to participate in the study
Exclusion criteria
Exclusion criteria: pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Induction of coma. Timepoint: Before injection and then for three days (three times a day: morning, noon and night shifts). Method of measurement: By bispectral index criteria. | — |
Secondary
| Measure | Time frame |
|---|---|
| Level of consciousness. Timepoint: Measure before injection and after injection daily (every 15 minutes) for 3 days. Method of measurement: Glasgow Criterion.;Vital signs. Timepoint: Measure before injection and after injection daily (every 15 minutes) for 3 days. Method of measurement: Monitoring device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNavid Kalani
Jahrom University of Medical Sciences
Outcome results
None listed