Diabetic Foot. Diabetes mellitus due to underlying condition with foot ulcer
Conditions
Interventions
Intervention 1: Intervention group: The treatment group (n= 35) including patients with grade 3 and 4 diabetic foot ulcers based on Wagner's classification. Curcumin (as C3 complex) at a dose of 500 m
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Signed informed consent form Patients with diabetic foot ulcer grade 3 and 4 according to the Wagner classification do not require surgery at this stage of wound healing. Patients with ischemic foot ulcer are not included in the study. Patients with pressure sore are not included in the study. If the patient has renal failure undergoing dialysis, he/she will not be included in the study.
Exclusion criteria
Exclusion criteria: Not referring the patient for subsequent follow-ups so that the nurse can not dress the wound (travel or change the patient's place of residence) Occurrence of any medical problem or surgery not related to wound healing that makes it impossible to continue the study (such as myocardial infarction or stroke, acute limb ischemia, sepsis for any reason other than the patient's wound and etc). Hepatic failure Biliary obstruction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing (wound healing by epithelialization). Timepoint: The depth of the wound will be evaluated before and 100 days after the intervention. Method of measurement: Wound depth is measured using the vernier caliper at the maximum vertical diameter of the wound and wound healing will be determined according to the Wagner criterion. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting Blood Glucose. Timepoint: Before and 100 days after the intervention. Method of measurement: Laboratory kit.;HbA1c. Timepoint: Before and 100 days after the intervention. Method of measurement: laboratory kit.;Insulin. Timepoint: Before and 100 days after the intervention. Method of measurement: laboratory kit.;Lipid Profile. Timepoint: Before and 100 days after the intervention. Method of measurement: laboratory kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Saberi-Karimian
Mashhad University of Medical Sciences
Outcome results
None listed