Skip to content

Survey the effect of magnesium citrate supplementation on clinical symptoms and TNF-a and hs-CRP factors in patients with COVID-19

Survey the effect of magnesium citrate supplementation on clinical symptoms and TNF-a and hs-CRP factors in patients with COVID-19

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210413050957N1
Enrollment
60
Registered
2021-05-01
Start date
2021-05-05
Completion date
Unknown
Last updated
2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

covid-19. COVID-19, virus identified.

Interventions

Intervention 1: Intervention group: The magnesium citrate supplement is taken as a 300 mg capsule once a day for 1 month. Intervention 2: Control group: The placebo is taken as a capsule containing 30

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Laboratory confirmation of Covid-19 (2019-nCoV Real-Time RT-PCR) Patients with moderate status Age from 18 to 65 years gender: male/female

Exclusion criteria

Exclusion criteria: Hospitalization of the patient in the intensive care unit Underlying diseases such as diabetes, hypertension, cardiovascular disease, kidney disease and mental disorders such as depression Obesity (BMI = 30) Vitamin D level less than 30 ng / ml Hypomagnesemia (magnesium level less than 1.7 mg / dL) and hypermagnesemia (magnesium level higher than 2.6 mg / dL) Pregnancy and lactation Contraindications, intolerance or allergy to magnesium Taking dietary supplements Alcohol and drug abuse

Design outcomes

Primary

MeasureTime frame
Cough. Timepoint: First and 30 days after the intervention. Method of measurement: Clinical examination.;Oxygen saturation. Timepoint: First and 30 days after the intervention. Method of measurement: using pulse oximeter device.;Respiratory rate. Timepoint: First and 30 days after the intervention. Method of measurement: Clinical examination.;Fever. Timepoint: First and 30 days after the intervention. Method of measurement: Clinical examination.;Rate of lung involvement. Timepoint: First and 30 days after the intervention. Method of measurement: CT scan of the chest.;Duration of hospitalization. Timepoint: First and 30 days after the intervention. Method of measurement: Counting the days of hospitalization.;Hs-CRP. Timepoint: First and 30 days after the intervention. Method of measurement: Based on laboratory measurements-mg/l.;TNF-a. Timepoint: First and 30 days after the intervention. Method of measurement: Based on laboratory measurements-mg/l.;CBC. Timepoint: First and 30 days after the intervention. Method of measurement: Cell counter.;Final status of the patient. Timepoint: First and 30 days after the intervention. Method of measurement: Dead / Alive.;Depression. Timepoint: First and 30 days after the intervention. Method of measurement: questionnaire scoring(BDI-II).;Anxiety. Timepoint: First and 30 days after the intervention. Method of measurement: questionnaire scoring(STAI).;Quality of Life. Timepoint: First and 30 days after the intervention. Method of measurement: questionnaire scoring(sf-36).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSepideh Rostami

Ahvaz University of Medical Sciences

sepidehrostami.nutrition@gmail.com+98 61 3441 2049

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 6, 2026