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Consequences of intratracheal administration of surfactant and surfactant with budesonide

Comparative survey of the consequences of intratracheal administration of surfactant and surfactant with budesonide in premature infants with respiratory distress syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210412050944N1
Enrollment
50
Registered
2021-06-01
Start date
2021-06-24
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Distress Syndrome.

Interventions

Intervention group 1: In infants that are under nasal continuous positive airway pressure and ventilator, gradually flow continues increase to CDP = 6 inches, H2O and FiO2 = 30%. A requirement of FiO2

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Days to 14 Days

Inclusion criteria

Inclusion criteria: Infants that have clinical signs of respiratory distress syndrome. Infants that their ages are have 2 weeks. Infants receiving nasal continuous positive airway pressure with surfactant.

Exclusion criteria

Exclusion criteria: Infants that have congenital anomalies. Infants that have perinatal asphyxia.

Design outcomes

Primary

MeasureTime frame
Percentage of infants with respiratory distress syndrome. Timepoint: Before the intervention and every 12 hours after the administration of surfactant in the intervention group and surfactant with budosonide 0.25 mg intratracheally in the control group. Method of measurement: Mechanical Ventilation Device.

Secondary

MeasureTime frame
Reduction of respiratory distress syndrome in preterm infants prescribed with surfactant and surfactant with budesonide. Timepoint: Before the intervention and every 12 hours after the administration of surfactant in the intervention group and surfactant with budosonide 0.25 mg intratracheally in the control group. Method of measurement: Mechanical Ventilation Devices.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Tohidnia

Qazvin University of Medical Sciences

cgd_rc@yahoo.com+98 28 3332 8709

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026