Efficacy of Lotion Containing Black Rice Bran (Oryza sativa L. indica) Extract as Skin Brightening Agent, a Clinical

Comparison of the Efficacy of Lotion Containing Black Rice Bran (Oryza sativa L. indica) Extract with Placebo as Skin Brightening Agent with in Healthy Asian Women

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210412050942N1

Enrollment

Registered

2021-05-01

Start date

2020-01-01

Completion date

Unknown

Last updated

2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy skin condition.

Interventions

Intervention 1: Intervention group: one lotion containing black rice bran extract 10% is applied in one side of volunteer's volar. each application of lotion is 0,5 gram, applied in diameter 5 centime

Eligibility

Sex/Gender

Female

Age

18 Years to 25 Years

Inclusion criteria

Inclusion criteria: healthy skin condition; Asian race

Exclusion criteria

Exclusion criteria: history of allergies; pregnant or breastfeeding; chronic medical history, have tattoos, scars or burns; currently using therapies such as anti-inflammatory, corticosteroids, hormonal contraceptives, or lasers; smoke, drink alcohol and use drugs, orally consume the test substance (black rice bran extract), apply and consume skin brightening agent topically or orally

Design outcomes

Primary

Measure	Time frame
Melanin index. Timepoint: 2 weeks after intervention. Method of measurement: Measure skin melanin index with mexameter.	—

Countries

Indonesia

Contacts

Public ContactAfifah Kusuma Vardhani

University of Indonesia

afifah.felani@gmail.com+62 622 74372722

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026