The effectiveness of cognitive-behavioral therapy (CBT) on positive and negative psychotic symptoms and emotional regulation in patients with schizophrenia spectrum disorders

The effectiveness of cognitive-behavioral therapy (CBT) on positive and negative psychotic symptoms and emotional regulation in patients with schizophrenia: A single-case pilot design for five patients with schizophrenia spectrum disorders

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210412050937N2

Enrollment

Registered

2021-12-14

Start date

2021-01-18

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia spectrum disorders. Schizophrenia

Interventions

Intervention group: Five patients with schizophrenia spectrum disorders participated in treatment sessions on a single-subject basis. The Cognitive-behavioral Therapy Manual consists of 16 sessions, e

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Diagnosis of schizophrenia spectrum disorders based on DSM5 criteria Relative control of acute symptoms of patients Average age 18 to 45 years Voluntary attendance with informed written consent Research Having a minimum education with a diploma certificate Receiving a higher score on PANSS and DERS scales Compared to other patients Patients who have been in the ward for at least one week

Exclusion criteria

Exclusion criteria: No criminal or judicial problems Alcohol or substance abuse Neurological disorders such as epilepsy, stroke or severe concussion High levels of disordered behavior or high risk of suicide or homicide Diagnosis Mental retardation. Severe learning disability

Design outcomes

Primary

Measure	Time frame
Positive and negative psychotic symptom score in Schizophrenia positive and negative symptom scale. Timepoint: Measures of The Positive and Negative Psychotic Symptoms two weeks before the start of the intervention (three baseline), all intervention sessions (16 Sessions), and 3 months after the end of the intervention (three follow-up lines). Method of measurement: The Positive and Negative Psychotic Symptoms Scale.;Emotional regulation score in the Gratz and Roemer Emotional Regulation Difficulties Scale. Timepoint: Measures of emotional regulation two weeks before the start of the intervention (three baseline), all intervention sessions (16 sessions), and 3 months after the end of the intervention (three follow-up lines). Method of measurement: Gratz and Roemer Emotional Regulation Difficulties Scale.	—

Measure

Time frame

Positive and negative psychotic symptom score in Schizophrenia positive and negative symptom scale. Timepoint: Measures of The Positive and Negative Psychotic Symptoms two weeks before the start of the intervention (three baseline), all intervention sessions (16 Sessions), and 3 months after the end of the intervention (three follow-up lines). Method of measurement: The Positive and Negative Psychotic Symptoms Scale.;Emotional regulation score in the Gratz and Roemer Emotional Regulation Difficulties Scale. Timepoint: Measures of emotional regulation two weeks before the start of the intervention (three baseline), all intervention sessions (16 sessions), and 3 months after the end of the intervention (three follow-up lines). Method of measurement: Gratz and Roemer Emotional Regulation Difficulties Scale.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Khakbaz

University of social welfare and rehabilitation sciences

khakbaz.hamid@gmail.com+98 21 5591 5322

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026