The effect of hops on female sexual function

Short -term effect of vaginal Hop (Humuluslupulus L.) on sexual function in women with menopausal symptoms

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210405050859N1

Enrollment

Registered

2021-07-18

Start date

2021-06-05

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menopause. Menopausal and female climacteric states

Interventions

Intervention 1: Intervention group: Vaginal estradiol 0.625 mg for 21 nights and 7 nights rest. Intervention 2: Intervention group: Razak vaginal extract (vaginal gel made in Iran and Barij Essential

Eligibility

Sex/Gender

Female

Age

45 Years to No maximum

Inclusion criteria

Inclusion criteria: All married women over the age of 45 who have had amenorrhea for at least a year and are experiencing menopause for the first time

Exclusion criteria

Exclusion criteria: Patients who are allergic to hops or estradiol Estrogen-dependent cancers Concomitant use of drugs that interfere with sexual function Underlying diseases including diabetes Liver disorders, seizures, and autoimmune diseases Smoking and alcohol consumption

Design outcomes

Primary

Measure	Time frame
Sexual desire. Timepoint: Before intervention and 4 weeks after starting the drug. Method of measurement: brief questionnaire measure of sexual functioning in women.;Sexual arousal. Timepoint: Before intervention and 4 weeks after starting the drug. Method of measurement: brief questionnaire measure of sexual functioning in women.;Sexual slippage. Timepoint: Before intervention and 4 weeks after starting the drug. Method of measurement: brief questionnaire measure of sexual functioning in women.;Orgasem. Timepoint: Before intervention and 4 weeks after starting the drug. Method of measurement: brief questionnaire measure of sexual functioning in women.;Sexual satisfaction. Timepoint: Before intervention and 4 weeks after starting the drug. Method of measurement: brief questionnaire measure of sexual functioning in women.;Pain during intercourse. Timepoint: Before intervention and 4 weeks after starting the drug. Method of measurement: Brief questionnaire measure of sexual functioning in women.	—

Measure

Time frame

Sexual desire. Timepoint: Before intervention and 4 weeks after starting the drug. Method of measurement: brief questionnaire measure of sexual functioning in women.;Sexual arousal. Timepoint: Before intervention and 4 weeks after starting the drug. Method of measurement: brief questionnaire measure of sexual functioning in women.;Sexual slippage. Timepoint: Before intervention and 4 weeks after starting the drug. Method of measurement: brief questionnaire measure of sexual functioning in women.;Orgasem. Timepoint: Before intervention and 4 weeks after starting the drug. Method of measurement: brief questionnaire measure of sexual functioning in women.;Sexual satisfaction. Timepoint: Before intervention and 4 weeks after starting the drug. Method of measurement: brief questionnaire measure of sexual functioning in women.;Pain during intercourse. Timepoint: Before intervention and 4 weeks after starting the drug. Method of measurement: Brief questionnaire measure of sexual functioning in women.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Vahedpour

Kashan University of Medical Sciences

zahravahedpoor@gmail.com+98 31 5544 3022

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 9, 2026