The effect of Cellen Plus capsules on vancomycin-induced nephrotoxicity.
Conditions
Interventions
Intervention 1: Intervention group: Selen Plus capsules every 12 hours for three days, manufactured by Iran under the license of Germany, whose ingredients are selenium 50ug, vitamin C 125mg, zinc 8mg
Sponsors
Sabzevar University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Months to 18 Years
Inclusion criteria
Inclusion criteria: Patients with systemic infection treated with vancomycin Complete the informed consent form
Exclusion criteria
Exclusion criteria: Concurrent renal failure Concomitant use of another nephrotoxic drug Patients with severe dehydration Patients with elevated urea and creatinine at baseline and initial testing
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine microalbumin. Timepoint: At the beginning of the study (before the intervention) and 72 hours after the start of taking Selen Plus capsules. Method of measurement: Urine tests. | — |
Secondary
| Measure | Time frame |
|---|---|
| Urea. Timepoint: At the beginning of the study (before the start of the intervention) and 72 hours after the start of taking Selen Plus capsules. Method of measurement: Blood test.;Creatine. Timepoint: At the beginning of the study (before the start of the intervention) and 72 hours after the start of taking Selen Plus capsules. Method of measurement: Blood test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactYosra Mohammadi Yazdi
Sabzevar University of Medical Sciences
Outcome results
None listed