Poor ovarian response. Ovarian dysfunction
Conditions
Interventions
Intervention 1: In this study, to compare the effect of luteal phase stimulation with follicular phase stimulation in patients with poor ovarian response, in the luteal phase group on days 15 to 16 of
Sponsors
Avicenna University Jihad Infertility Center Avicenna
Eligibility
Sex/Gender
Female
Age
18 Years to 39 Years
Inclusion criteria
Inclusion criteria: History of an ovulation stimulation cycle with less than 4 oocytes AMH<1.1 ng/ml or AFC<5 The total number of motile sperm is at least 15 million Normal uterus in ultrasound and hysterosalpingography Regular periods of 21-35 days Indication for IVF Ability to participate and collaborate with study protocol Signature informed consent Under 40 years
Exclusion criteria
Exclusion criteria: History of ovarian surgery History of pelvic cytotoxic radiation exposure due to malignancy History of recurrent miscarriage Grade III or IV endometriosis Concomitant uterine pathology (adenomyosis, submucosal myoma, Asherman syndrome) Autoimmune disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of metaphase II oocyte. Timepoint: End of ovarian stimulation. Method of measurement: Observation of metaphase 2 oocytes extracted by the embryologist. | — |
Secondary
| Measure | Time frame |
|---|---|
| Chemical pregnancy rate. Timepoint: 14 days after transfer. Method of measurement: Beta-Human Chorionic Gonadotropin.;Clinical pregnancy. Timepoint: Pregnancy 7th weeks. Method of measurement: Detect of fetal heart beat on ultrasound.;Total number of embryos. Timepoint: After in vitro fertilization. Method of measurement: 18-20 hours after in vitro fertilization. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMozhgan Vahabi Dastjerdi
Avicenna infertility clinic
Outcome results
None listed