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Evaluation of the effect of oral azithromycin on COPD patients

Effects of Adding Azithromycin to Standard Outpatient and Inpatient COPD Treatment in Shahrekord University of Medical Sciences Hospitals

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210405050849N1
Enrollment
100
Registered
2021-05-28
Start date
2021-06-22
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease. Chronic obstructive pulmonary disease, unspecified

Interventions

Intervention 1: Control group: Patients in the control group receive conventional therapy (triple therapy) and placebo. Triple therapy includes inhaled anticholinergics (long-acting, short-acting), in

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Diagnosis of COPD by an internal medicine physician, based on the classification of global pioneers of chronic obstructive pulmonary disease (GOLD) No other chronic diseases such as orthopedic and motor diseases, multiple sclerosis or cancer. hospitalization stability of the patient's physical and mental condition

Exclusion criteria

Exclusion criteria: Lack of motivation of the patient to cooperation Immune system defects (recurrent respiratory infections and worsening of shortness of breath) Existence of concomitant asthma Complications of azithromycin non-pulmonary diseases like cancer; liver dysfunction, cholestatic jaundice, Infiltration and consolidation in chest x-ray Patients with acute exacerbation of COPD Existence of atopy or allergic rhinitis pneumonia embolism Kidney failure hearing loss

Design outcomes

Primary

MeasureTime frame
FEV1/ FVC. Timepoint: Two months after starting the study. Method of measurement: Spirometry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEbrahim Abbasi Monjezi

Shahre-kord University of Medical Sciences

st-abbasi.e@skums.ac.ir+98 38 3222 0016

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026