Adjusting opioide use

Evaluation of the effect of gabapentin against clonidine in reducing the dose of sedation in patients with mechanical artificial ventilation

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210405050848N2

Enrollment

Registered

2021-06-13

Start date

2021-07-23

Completion date

Unknown

Last updated

2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adjust opioid use. Opioid overdose

Interventions

Intervention 1: Intervention group: Gabapentin 300 mg tablets are gavaged three times a day. Fentanyl ampoules are also given as a PRN at 25 to 200 micro / hour infusion. We record the need for fentan

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Patients connected to a mechanical ventilator

Exclusion criteria

Exclusion criteria: History of Clonidine allergy History of Gabapentine allergy

Design outcomes

Primary

Measure	Time frame
Sedation of patients connected to a mechanical ventilator. Timepoint: Before and after medication. Method of measurement: Ramsay score.	—

Secondary

Measure	Time frame
Adjustment Opioide use. Timepoint: Before and after medication. Method of measurement: Ramsay score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJafar Vakili

Shahid Beheshti University of Medical Sciences

jafar.vakili@sbmu.ac.ir+98 21 2243 9770

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026