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paracetamol and lidocaine in pain of intravenous propofol

Comparative study of prophylactic effect of injectable paracetamol and lidocaine on pain caused by intravenous injection of propofol in children 6 to 10 years

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210403050824N1
Enrollment
90
Registered
2021-07-11
Start date
2021-07-21
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain induced by intravenous propofol injection.. Other complications of anesthesia

Interventions

Intervention 1: The first intervention group: All patients have been taken to the operating room then after premedication with 0.1 milligram per kilogram of midazolam, intravenous cannula number 20 ha

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 10 Years

Inclusion criteria

Inclusion criteria: Children 6 to 10 years general anesthesia with propofol ASA1,ASA2

Exclusion criteria

Exclusion criteria: Known liver disease Known heart disease Known neurological disease History of metabolic disease Drug reactions and allergies

Design outcomes

Primary

MeasureTime frame
Patient pain score at baseline and one minute after propofol injection. Timepoint: At baseline when injecting propofol and one minute after injecting propofol. Method of measurement: Propofol injection pain score based on the patient's motor and verbal response.;Heart rate at baseline and one minute after propofol administration. Timepoint: At baseline and one minute after propofol injection. Method of measurement: Saadat Standard monitoring.;Mean arterial pressure at baseline and one minute after propofol injection. Timepoint: At baseline and one minute after propofol injection. Method of measurement: Saadat Standard monitoring.;Patient agitation during propofol injection. Timepoint: At baseline and one minute after propofol injection. Method of measurement: Richmond Agitation scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmad Karimi hasan abadi

Esfahan University of Medical Sciences

ahmadkarimi1886@gmail.com+98 31 4274 3155

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026