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Comparison of the effect of Ibuprofen and Piroxicam on pain relief after surgery

Comparison of the prophylactic effectiveness of intravenous Ibuprofen and intramuscular Piroxicam on pain intensity after lower abdominal surgery under general anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210331050801N1
Enrollment
90
Registered
2021-07-12
Start date
2021-08-01
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain. Other acute postprocedural pain

Interventions

Intervention 1: Intervention group: Immediately after induction of anesthesia (which is the same in all 3 groups) and before surgical incision, 20 mg Piroxicam (made by Alborz daroo factory) is inject

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: ASA1 and ASA2 patient Patient aged 25 to 65 years Patients undergoing lower abdominal surgery No history of drugs, alcohol and benzodiazepine addiction No history of seizures, psychiatric problems, liver and kidney disease, gastrointestinal bleeding, peptic ulcer and Coagulation disorder No allergy to the drugs used in the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Intensity of postoperative pain. Timepoint: Immediately after consciousness in recovery and 2, 8, 12 and 24 hours after surgery. Method of measurement: visual analogue scale.;The amount of opioid used in the first 24 hours after surgery. Timepoint: First 24 hours after surgery. Method of measurement: Reading the patient file.;Blood pressure. Timepoint: At the beginning of surgery and then every 30 minutes during surgery. Method of measurement: Digital barometer.;Heart rate. Timepoint: At the beginning of surgery and then every 30 minutes during surgery. Method of measurement: Pulse oximeter.;Duration of stay in recovery. Timepoint: After leaving the recovery. Method of measurement: Minute.;Extubation time. Timepoint: After extubation. Method of measurement: Minute.;The first time of requesting opioid after surgery. Timepoint: After end of surgery. Method of measurement: Minute.;Degree of patients' satisfaction with pain relief. Timepoint: 24 hours after surgery. Method of measurement: Use of visual analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGholamreza Khalili

Esfahan University of Medical Sciences

khalili@med.mui.ac.ir+98 31 3620 1992

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026