acute anticholinestrase pesticide poisoning. Poisoning by, adverse effect of and underdosing of anticholinesterase agents
Conditions
Interventions
Intervention 1: Intervention group (Group I): 40 patients will be enrolled. They will receive albuterol (The albuterol used in this trial is Farcolin Respirator Solution made by PHARCO Pharmaceuticals
Sponsors
Tanta Faculty of Medicine
Eligibility
Sex/Gender
All
Age
12 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients (male or female, aged 12 years or older) with moderate or severe acute anticholinesterase poisoning
Exclusion criteria
Exclusion criteria: Age less than 12 years old Pregnancy Lactation Ingestion or exposure to other substances in addition to the anticholinesterase agent Presence of other major medical conditions (e.g. respiratory or cardiovascular diseases, renal or hepatic failure) Delay more than 12 hours since exposure to the anticholinesterase agent (late presenters) Asymptomatic or mild poisoning with anticholinesterase agents Receiving unreported treatment before admission to our center
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygen saturation. Timepoint: From the start of intervention up to 60 minutes after intervention. Method of measurement: Pulse oximetry and arterial blood gas measurement. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality. Timepoint: From admission till the discharge of patient. Method of measurement: Clinical evaluation.;Need for mechanical ventilation. Timepoint: From admission till the discharge of patient. Method of measurement: Clinical evaluation.;Length of hospital stay. Timepoint: From admission till the discharge of patient. Method of measurement: Total number of hours passed from admission till discharge.;The time needed for atropinization and the dose of atropine required for full atropinization . Timepoint: From the time of atropine administration until full atropinization occurs. Method of measurement: Clinical evaluation. | — |
Countries
Egypt
Contacts
Public ContactDr. Samar youssef
Tanta Faculty of Medicine
Outcome results
None listed