Effect of sodium levothyroxine on Electrocardiographic findings (QTc and QTd)

Effect of sodium levothyroxine on Electrocardiography findings(QTc & QTd) of subclinical hypothyroidism patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210331050794N1

Enrollment

200

Registered

2021-05-15

Start date

2021-05-22

Completion date

Unknown

Last updated

2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subclinical hypothyroidism. Subclinical iodine-deficiency hypothyroidism

Interventions

Intervention 1: Intervention group: will receive 50 micrograms of levothyroxine sodium daily for 3 months . Intervention 2: Control group: Includes patients with subclinical hypothyroidism with a TSH

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: TSH levels greater than 5 nanograms per deciliter and normal thyroid hormones QTc greater than 460 ms absence of heart disease Age range 20-50 years

Exclusion criteria

Exclusion criteria: Pregnancy or hormonal disorder Taking drugs that affect the QTc interval

Design outcomes

Primary

Measure	Time frame
Change in QTc&QTd interval. Timepoint: QTc & QTd measurements will be performed before the intervention and 3 months after receiving the intervention. Method of measurement: QTc & QTd measurements will be performed using electrocardiography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAsadollah Amiripour

Kermanshah University of Medical Sciences

asadamiri1351@yahoo.com+98 83 3838 6835

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026