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Comparative study of morphine effect by intranasal and intravenous methods in orthopedic surgeries

Comparative study of morphine effect by intranasal and intravenous methods in orthopedic surgeries in the upper limb

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210328050784N1
Enrollment
78
Registered
2021-04-13
Start date
2021-04-21
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthopedic surgeries on the upper limbs.

Interventions

Intervention 1: Intervention group: First: Use of 2 cc morphine by intravenous injection in recovery to relieve patient pain. Intervention 2: Intervention group: Second: using 2 cc of morphine by intr

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidate for orthopedic surgery for upper limb fractures under general anesthesia Agree to participate in the study Natural GCS (score 15) based on the Glasgow scale Weight between 60 to 100 kg Duration of operation up to 3 hours No underlying diseases including diabetes, liver and kidney disease, COPD and coagulation disorders Lack of sensitivity to drugs No addiction No head injuries during the accident More than 12 breaths per minute Systolic blood pressure greater than 110 mm Hg SPO2 More than 95% in room air

Exclusion criteria

Exclusion criteria: Dissatisfaction with continuing to participate in the project Prolongation of surgery time more than 3 hours

Design outcomes

Primary

MeasureTime frame
Postoperative pain. Timepoint: 10, 30, 60 minutes and 2 and 4 hours after drug administration. Method of measurement: VAS scale.;Nausea. Timepoint: 10, 30, 60 minutes and 2 and 4 hours after drug administration. Method of measurement: VAS Nausea Scale.;Vomiting. Timepoint: 10, 30, 60 minutes and 2 and 4 hours after drug administration. Method of measurement: Frequent vomiting: Less than once: Mild,Between 1-3 times: Medium,More than 3 times or howling: severe.;Itching. Timepoint: 10, 30, 60 minutes and 2 and 4 hours after drug administration. Method of measurement: Asking: yes / no.;Vertigo. Timepoint: 10, 30, 60 minutes and 2 and 4 hours after drug administration. Method of measurement: Asking: yes / no.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasrin Ghaffari vasati

Mazandaran University of Medical Sciences

nasringhaffari.amo@gmail.com+98 11 4422 4002

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026