Evaluation of the effectiveness of flavonoid lotion in the treatment of hemorrhoids

Evaluation of the efficacy and safety of an innovative flavonoid lotion in patients with hemorrhoid; A Randomized Clinical Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210325050769N2

Enrollment

100

Registered

2021-12-27

Start date

2020-04-20

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemorrhoids. Hemorrhoids and perianal venous thrombosis

Interventions

Intervention 1: Intervention group: Patients in this groups use the herbal lotion topically/rectal, twice a day for one month. Each 100 mg of produced flavonoid lotion has 70% flavonoid content (1/2 h

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with grade 2 or higher hemorrhoids Age range 18-75 Lack of drug allergy to lotion Lack of confounding underlying disease such as diabetes Patient satisfaction

Exclusion criteria

Exclusion criteria: Patient dissatisfaction Higher or lower grades of disease Presence of drug allergy to plant Lotion Existence of confounding underlying disease such as diabetes

Design outcomes

Primary

Measure	Time frame
Hemorrhoid grade. Timepoint: weekly. Method of measurement: With history and physical examination.;Rectal bleeding. Timepoint: Weekly. Method of measurement: With history and physical examination.;Anal pain. Timepoint: Weekly. Method of measurement: With history and physical examination.;Incomplete defecation. Timepoint: Weekly. Method of measurement: With history and physical examination.;Anal irritation. Timepoint: Weekly. Method of measurement: With history and physical examination.;Anal discharge. Timepoint: weekly. Method of measurement: With history and physical examination.;Anal discomfort. Timepoint: Weekly. Method of measurement: With history and physical examination.	—

Measure

Time frame

Hemorrhoid grade. Timepoint: weekly. Method of measurement: With history and physical examination.;Rectal bleeding. Timepoint: Weekly. Method of measurement: With history and physical examination.;Anal pain. Timepoint: Weekly. Method of measurement: With history and physical examination.;Incomplete defecation. Timepoint: Weekly. Method of measurement: With history and physical examination.;Anal irritation. Timepoint: Weekly. Method of measurement: With history and physical examination.;Anal discharge. Timepoint: weekly. Method of measurement: With history and physical examination.;Anal discomfort. Timepoint: Weekly. Method of measurement: With history and physical examination.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Razdar

Bagheiat-allah University of Medical Sciences

Srazdar@gmail.com+98 21 8861 2072

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026