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Effect of Neostigmine and Atropine on post dural puncture headache in spinal anesthesia in cesarean

Effect of pre-administration with Neostigmine and Atropine on the occurrence of post dural puncture headache in patients undergoing spinal anesthesia in cesarean

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210324050762N1
Enrollment
62
Registered
2021-09-24
Start date
2021-08-22
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cesarean section. Delivery by caesarean section, unspecified

Interventions

Intervention 1: Intervention group: All patients will undergo spinal block. After performing the spinal block and confirming its accuracy, patients will be prescribed a combination of 0.5 mg of neosti

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Pregnant woman candidate for cesarean section with spinal anesthesia American anesthesiologists association classification I and II Age 18-45 years No neurological deficit in limb, spinal cord and CNS No coagulation diseases No history of spinal cord surgery, spinal canal stenosis and MS Duration of surgery less than 2 hours No heart conductive disorder No history of migraine headaches No anticoagulant drug consumption Consent for spinal block Patient consent to participate in the study

Exclusion criteria

Exclusion criteria: Spinal block failure Change in anesthesia method to general anesthesia Bleeding more than 20 cc/kg More than 3 punctures

Design outcomes

Primary

MeasureTime frame
Headache severity. Timepoint: From first day to five days after surgery. Method of measurement: Visual Analogue Scale (VAS).;Duration of headache. Timepoint: From first day to five days after surgery. Method of measurement: Counting the number of days suffering from headache.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactLili Adineh Mehr

Esfahan University of Medical Sciences

liliadineh@yahoo.com+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026