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Evaluation of the effect of Heparin alone and in combination with Vancomycin and Amikabisen in the prevention of tunnel catheter infection

Comparative study of the effect of Heparin alone or in combination with Amikacin and Vancomycin antibiotics in the prevention of infection caused by tunnel central catheters in patients with renal insufficiency undergoing hemodialysis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210317050735N1
Enrollment
60
Registered
2023-01-04
Start date
2023-02-20
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

End stage renal disease. End stage renal disease

Interventions

Intervention 1: Intervention group A: Patients undergoing hemodialysis who have recently had a tunneled central venous catheter installed will enter group A after obtaining consent. In this group, at

Sponsors

Ardabil University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Insertion of a new central tunnel catheter for hemodialysis Absence of inflammation in the vascular access area at the beginning of the study At least 2 months after starting dialysis Perform 2 or 3 dialysis sessions per week Being over 18 years old No specific diseases such as Leukemia, Infection, Immunodeficiency, Dermatitis

Exclusion criteria

Exclusion criteria: Having an infectious disease in other parts of the body Antibiotic use in the previous two weeks

Design outcomes

Primary

MeasureTime frame
Incidence of catheter-related infections in patients under hemodialysis. Timepoint: Six-month follow-up of the two groups. Method of measurement: Blood culture to evaluate for catheter-related infection.

Secondary

MeasureTime frame
Fever. Timepoint: During the 6-month follow-up period. Method of measurement: fever measurement.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Iranikia

Ardabil University of Medical Sciences

Dr.maryam.1983@gmail.com+98 45 3373 2886

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026