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The effect of the metformin in preventing of the preeclampsia

Evaluation of the effect of metformin in prevention from severe preeclampsia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210316050725N1
Enrollment
52
Registered
2021-05-28
Start date
2021-06-05
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non severe preeclampsia. Mild to moderate pre-eclampsia, unspecified trimester

Interventions

Intervention 1: In the intervention group, pregnant woman with only high blood pressure is given 1000 mg of metformin during her entire pregnancy, and during the course of labor, the symptoms of sev

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Non severe preeclampsia Single pregnancy

Exclusion criteria

Exclusion criteria: Eclamsia Severe reeclamsia Renal failure Insulin -treated diabet

Design outcomes

Primary

MeasureTime frame
Severe preeclampsia. Timepoint: Weekly untill term pregnancy. Method of measurement: Weekly visit , blood pressure assesment , laboratory assesment.

Secondary

MeasureTime frame
Hypertension. Timepoint: Weekly visit. Method of measurement: with the help of mercury manometer.;Fetal growth. Timepoint: Weekly. Method of measurement: Ultrasound.;Elevated in liver enzyme. Timepoint: Weekly. Method of measurement: Laboratory.;Headache, blurred vision , pain in epigaster. Timepoint: weekly. Method of measurement: Biography.;Blood creatinine in mother. Timepoint: Weekly. Method of measurement: Laboratory.;Diabet in mother. Timepoint: Monthly. Method of measurement: Assesment of Fast blood sugar and 2 hours after meal.;Fetal health assessment tests. Timepoint: Weekly. Method of measurement: Non stress test and biophysical profile.;Proteinurea. Timepoint: Weekly. Method of measurement: By collecting urine 24 hours a day.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahnaz Ahmadi

Iran University of Medical Sciences

Ahamdishahnaz2005@yahoo.com+98 21 5563 3244

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026