Comparing Effect of Gabapentin and Caffeine on Treatment of Headache Following Spinal Anesthesia

Comparing Effect of Gabapentin and Caffeine on Treatment of Headache Following Spinal Anesthesia in Women Candidate for Cesarean Section

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210314050703N2

Enrollment

Registered

2021-06-15

Start date

2021-06-22

Completion date

Unknown

Last updated

2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post dural puncture headache. Other headache syndromes

Interventions

Intervention 1: Intervention group 1: Administration of 300 mg capsule of gabapentin(Mehr Darou- Tehran- Iran) orally every 12 hours for 3 days in patients after cesarean section with a history of po

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Being in level 1 and 2 of the ASA classification system Incidence of post dural puncture headache Elective cesarean section surgery

Exclusion criteria

Exclusion criteria: History of co-existing diseases such as asthma, cardiovascular disease, diabetes. History of caffeine or gabapentin allergy Need for other painkillers (such as acetaminophen) during the study period Preeclampsia and eclampsia History of chronic headaches and migraines

Design outcomes

Primary

Measure	Time frame
Headache. Timepoint: At intervals of 24, 48 and 72 hours after starting treatment. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNegin Ghadami

Sanandaj University of Medical Sciences

ghadaminegin@gmail.com+98 87 3324 8519

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026