Acute Postoperative Pain. Acute cholecystitis
Conditions
Interventions
Intervention 1: Intervention group: Patients receiving pregabalin (capsule, 150 mg, product by Sobhan company, one time, oral, as single dose 2 hours before starting surgery) with celecoxib (capsule,
Sponsors
Shahre-kord University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Existence of ultrasonographic results confirming the presence of gallstones Symptomatic gallstone disease Candidate for elective surgery for laparoscopic cholecystectomy ASA Class 1 and 2 Age between 20 and 65 years Satisfaction to participate in the study
Exclusion criteria
Exclusion criteria: Dissatisfaction with participating in the project History of diseases affecting vital signs including heart and lung failure Confirmed malignancy Need an open cholecystectomy People older than 65 years History of Addiction Occurrence of unwanted complications during the operation People with contraindications to anesthesia or opioids (patients with known hypersensitivity to the compounds of various anesthetics) Patients with inability to answer visual pain ruler questions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patients' pain score based on visual and descriptive numerical pain questionnaire. Timepoint: Measurement of patients' pain, immediately after waking up in recovery, two and four hours after surgery. Method of measurement: Visual Analog Scale questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| The need for Narcotic Analgesics after surgery. Timepoint: Immediately after waking up in recovery, two to four hours after surgery. Method of measurement: Mg Morphin.;Hemodynamic symptoms. Timepoint: Immediately after waking up in recovery, two to four hours after surgery. Method of measurement: By measuring heart rate, pulse oximetry, respiratory rate, using blood pressure device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHossein Madineh
Shahre-kord University of Medical Sciences
Outcome results
None listed