Survey the effect of glasthma in asthma

The effect of glasthma ( traditional persian medicine product based on Glycyrrhiza glabra) ) on respiratory symptoms, spirometry test results and intestinal permeability index( lactolose / manitol ratio) in patients with asthma in comparison with placebo

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210309050643N2

Enrollment

Registered

2021-07-19

Start date

2021-07-23

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

asthma. Moderate persistent asthma

Interventions

Intervention 1: Intervention group: Patients receive 15 ml of Glasthma syrup, including aqueous extract of licorice, jujube, quince, echium and hazelnuts, divided into two parts in the morning and eve

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Moderate asthma diagnosed by a specialist Asthma for more than 6 months FEV1 60-80%

Exclusion criteria

Exclusion criteria: Cognitive diseases History of convulsive disease Using oral or systemic corticosteroids Pregnancy or breastfeeding Need to be hospitalized for any reason Smoking Exacerbation of the disease at the beginning of the study Hypertension or diabetes

Design outcomes

Primary

Measure	Time frame
Changes in patients' clinical symptoms. Timepoint: At the beginning and 4 weeks after the drug intervention. Method of measurement: International Asthma Registration Questionnaire.;Changes in respiratory test results. Timepoint: At the beginning and 4 weeks after the drug intervention. Method of measurement: Spirometry.;Changes in intestinal permeability. Timepoint: At the beginning and 4 weeks after the drug intervention. Method of measurement: lactolose/manitol ratio in urine.	—

Measure

Time frame

Changes in patients' clinical symptoms. Timepoint: At the beginning and 4 weeks after the drug intervention. Method of measurement: International Asthma Registration Questionnaire.;Changes in respiratory test results. Timepoint: At the beginning and 4 weeks after the drug intervention. Method of measurement: Spirometry.;Changes in intestinal permeability. Timepoint: At the beginning and 4 weeks after the drug intervention. Method of measurement: lactolose/manitol ratio in urine.

—

Secondary

Measure	Time frame
Changes in patients' quality of life. Timepoint: First and 4 weeks after drug intervention. Method of measurement: International Asthma Registration Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr shahin saeidinejat

Mashhad University of Medical Sciences

Saeedish1@mums.ac.ir+98 51 3884 8931

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026