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Effect of Lactogum Probiotic on Halitosis

Evaluation of the Effect of Lactogum Probiotic on Halitosis: A Randomized Controlled Clinical Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210306050606N4
Enrollment
70
Registered
2026-05-03
Start date
2026-03-04
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Halitosis. Halitosis

Interventions

Intervention 1: Intervention Group:The intervention group will receive oral hygiene education, and tongue cleaning using a toothbrush from back to front will be demonstrated. Furthermore, as per the m

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Age 18 to 55 years Concentration of volatile sulfur compounds greater than 150 parts per billion (measured by instrument) Tongue coverage index (TCI) greater than 50% Absence of tooth decay and periodontal disease, apical periodontitis, poor restorations and impacted wisdom teeth, non-smoking Absence of systemic disease, including diabetes, liver disease, and kidney disease, which can cause halitosis No use of antibiotics or mouthwash in the past two weeks Lack of fixed orthodontic appliances, mouth breathing, and dry mouth

Exclusion criteria

Exclusion criteria: Pregnancy, sinusitis, tonsillitis, digestive problems Taking medications such as paracetamol [acetaminophen], chloral hydrate, dimethyl sulfoxide, amphetamines, containing eucalyptus and arsenic

Design outcomes

Primary

MeasureTime frame
Severity of halitosis. Timepoint: Patient assessments were conducted at three time points: before the intervention, 4 weeks after the intervention ended, and 8 weeks after the intervention ended. Method of measurement: The Volatile Sulfur Compound Index is measured with the ShowNovo WG1 Portable Halitometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAdeleh Pooyafard

Yazd University of Medical Sciences

a.pooyafard@ssu.ac.ir+98 35 3620 4760

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026