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Comparison of the effect of Platelet-rich plasma and ozone gas injection in patients with temporomandibular joint disorders

Comparison of the effect of Platelet-rich plasma and ozone gas injection in patients with temporomandibular joint disorders

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210306050604N3
Enrollment
40
Registered
2022-02-19
Start date
2022-02-20
Completion date
Unknown
Last updated
2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporomandibular joint disorders.

Interventions

Intervention 1: Intervention group: Intervention group 1: For each joint, 10 cc of blood is taken from the patient's antecubital vein and transferred to sterile test tubes (BD Company-made in USA) co

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: A history of chronic temporomandibular joint pain and a clicking sound in one or both sides and decreased mouth opening that started at least 3 months ago and has not responded to conservative treatment No evidence of intra-articular pathological problems on open and closed-mouth dynamic MRI Do not have inflammatory connective tissue disease, neurological disorders, severe anemia, thrombocytopenia or malignant diseases of the head and neck Do not have masticatory muscles problems and muscle tenderness and a previous history of open surgery of tmj Do not have problems with dental origin in panoramic

Exclusion criteria

Exclusion criteria: Patients who do not agree with the injection protocol

Design outcomes

Primary

MeasureTime frame
Patient pain in temporomandibular joint. Timepoint: Days 0 (before the start of the study), 14, 30, 60. Method of measurement: Visual Analogue Scale ( VAS ).;Maximum mouth opening rate. Timepoint: Days 0 (before the start of the study), 14, 30, 60. Method of measurement: millimeter.;Joint clicking sound. Timepoint: Days 0 (before the start of the study), 14, 30, 60. Method of measurement: 0: No sound- 1: Subjective sound / can be heard with a stethoscope- 2: A sound that can be heard without a stethoscope.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Barzegar

Yazd University of Medical Sciences

m.Barzegar@ssu.ac.ir+98 35 3820 8342

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026