Burn. Burns classified according to extent of body surface involved
Conditions
Interventions
Intervention 1: Intervention group: The intervention group will receive 20% human albumin 0.125 milliliters per kilogram body weight per percent body surface burn between 8 to 12 hours after admission
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to No maximum
Inclusion criteria
Inclusion criteria: burn patients with 2nd and 3rd degree burn area more than 20 percent TBSA full-thickness burn area more than 10 percent TBSA patients needing vasopressor usage in the first 24 hours of admission patients needing intubation and mechanical ventilation in the first 24 hours of admission
Exclusion criteria
Exclusion criteria: patients not needing albumin infusion according to the clinical decision of specialist critically ill patients with expected death in first 24 hours or patients that expired in first 24 hours of admission brain death in first 24 hours patients admitted more than 8 hours after burn patients with chronic underlying diseases affecting serum albumin level, including nephrotic syndrome, cirrhosis, malnutrition, exudative enteropathy pregnancy a history of cardiac surgery or myocardial infarction in recent 5 years patients with high-voltage electrical burn injuries patient does not accept entering the study patients receiving plasmaphresis a history of reaction to human albumin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fluid creep, patient's fluid intake exceeding estimated intake with parkland formula. Timepoint: 12 hours and 1,2,3,5, and 7 days after-burn. Method of measurement: assessment of the fluid intake of patient to maintain a satisfactory urine output. | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of hospital stay. Timepoint: At the time of hospital discharge. Method of measurement: Days. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammadreza Mobayen
Rasht University of Medical Sciences
Outcome results
None listed