Polycystic ovarian syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention 1: Intervention group: Intake of 6 mg of melatonin (two tablets of 3 mg supplement of Nature Made, USA) one hour before bedtime, for 8 weeks. Intervention 2: Control group: Daily intake o
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Women with PCOS 18-40 years old BMI 20-40 Willingness to cooperate
Exclusion criteria
Exclusion criteria: Pregnancy Lactation Sleep disturbance Shift work Metabolic disease Taking drugs that cause or affect the symptoms of polycystic ovary syndrome Taking drugs that affect insulin sensitivity Takeing antioxidant supplements Following a special diet Losing weight more than 5% of current weight in the last 6 months Cigarettes and alcohol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visfatin. Timepoint: At the beginning of the study and 8 weeks later. Method of measurement: ELISA kit.;Fasting blood sugar. Timepoint: At the beginning of the study and 8 weeks later. Method of measurement: Spectrophotometry.;Insulin. Timepoint: At the beginning of the study and 8 weeks later. Method of measurement: ELISA kit.;Insulin sensitivity. Timepoint: At the beginning of the study and 8 weeks later. Method of measurement: The quantitative insulin-sensitivity check index formula (QUICKI). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFakhrosadat Fayazi
Tabriz University of Medical Sciences
Outcome results
None listed