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Comparison of the effect of ibuprofen and curcumin on pain control after mandibular third molar surgery

Comparison of the effect of ibuprofen and curcumin on pain control after mandibular third molar surgery

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210223050469N1
Enrollment
48
Registered
2021-02-28
Start date
2021-04-03
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extraction surgery of the third mandibular molar..

Interventions

Intervention 1: Intervention group: 24 subjects will be given curcumin at a dose of 200 mg from Nanosina Exir Company one hour before surgery and after observing the first sign of pain after surgery.

Sponsors

Vice Chancellor for Research, Islamic Azad University, Tehran Dental Branch
Lead Sponsor

Eligibility

Sex/Gender
All
Age
17 Years to 35 Years

Inclusion criteria

Inclusion criteria: The patient is fully satisfied to participate in the study People between 17 and 35 years old Indications for surgical extraction of the third mandibular molar Their latency conditions are the same

Exclusion criteria

Exclusion criteria: acute or chronic pericoronal inflammation. use of drugs other than the drug under study. incomplete or non-delivery of the questionnaire. systemic problems. pregnancy. contraindications to the drugs used in the study. having neurological diseases . Taking corticosteroids, antidepressants, antibiotics and analgesics.

Design outcomes

Primary

MeasureTime frame
Pain intensity after surgery. Timepoint: The patient takes the drug after seeing the first sign of pain after surgery and will announce the severity of the pain one hour after taking the drug. Method of measurement: The amount of pain will be recorded in the Visual Analogue Scale system.;Duration of analgesia. Timepoint: The duration of analgesia will be measured from one hour before surgery when the patient takes the first dose of the drug until the first sign of pain after surgery. Method of measurement: It will be measured in minutes.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactVahid Mesgarzadeh

Islamic Azad University

Vahid_mesgar@yahoo.com+98 21 2256 4571

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026