COVID-19 disease. COVID-19
Conditions
Interventions
Intervention 1: Intervention group 1: hospitalized patients with COVID-19 who take 60 mg intravenous Methylprednisolone in two divided dose, maximum 10 days in addition to standard treatment. Interve
Sponsors
Shahre-kord University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patient with COVID-19 Under 80 y/o age With positive RT-PCR test With bilateral lung parenchyma infiltration Blood oxygen saturation <93% Did not take any medication or hospitalization for COVID-19 Taking any Corticosteroid They have tendency to participate in this study
Exclusion criteria
Exclusion criteria: Patient leave hospital before discharge Patient who expire in first 24 hour after admission Patient with myocardial infarction during hospitalization Patient with underlying disease who have contraindication of corticosteroid such as acute hepatitis, fungal infection All patient who disagree to continue the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood oxygen saturation. Timepoint: In admission. Method of measurement: pulse oxymeter.;Duration of hospitalization. Timepoint: From admission to discharge. Method of measurement: Obsevation.;Duration between onset of symptom to start of corticosteroid. Timepoint: Before admission to start of drug. Method of measurement: Patient history. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality rate after 28 day. Timepoint: From admission to 28 day later. Method of measurement: Observation.;Number of oxygen dependency days. Timepoint: From admission to oxygen dependency time. Method of measurement: Observation.;Number of patient who need ICU admission. Timepoint: During hospitalization. Method of measurement: Obsevation.;Lab data. Timepoint: During admission , hospitalization and discharge. Method of measurement: Laboratory. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMarziyeh dehghani
Shahre-kord University of Medical Sciences
Outcome results
None listed