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Level of Metalloproteinase Matrix 8 in Gingival Crevicular Fluid of Mandibular anterior teeth with two types of fixed and removable orthodontic retainers

Level of Metalloproteinase Matrix 8 in Gingival Crevicular Fluid of Mandibular anterior teeth with two types of fixed and removable orthodontic retainers

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210221050435N2
Enrollment
30
Registered
2021-10-07
Start date
2021-07-01
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mandibular Retainer at the end of Orthodontic treatment.

Interventions

Intervention 1: Intervention group: After setting the appointment, for each patient in a session, the ESSIX retainer will be placed in the upper jaw, and according to the group in which they are plac

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients have been treated with the 022 System and their treatment has been completed with satisfactory correction of malocclusion and appropriate dental alingment. The Patient's condition is favorable in terms of general health. Absence of Craniofacial Syndromes and Facial Clefts Absence of severe and uncontrolled Caries The Patient should have good oral hygiene and be Periodontally normal. The Patient should have all the anterior Mandibular teeth and the teeth should be of normal shape and size.

Exclusion criteria

Exclusion criteria: Lack of Patient cooperation to refer Observe poor Periodontal status during the study Break and not using the retainer Specific conditions of COVID 19 infection that prevent the Patient from visiting.

Design outcomes

Primary

MeasureTime frame
Level of Matrix Metalloproteinase 8 after Orthodontic debonding. Timepoint: Immediately after debonding, 30 days after debonding, 90 days after debonding. Method of measurement: Sampling of the gingival crevice fluid will be done and then the amount of Matrix Metalloproteinase 8 enzyme will be determined with the kit related to the this enzyme .

Secondary

MeasureTime frame
Little irregularity index. Timepoint: Day of debonding, 30 days after debonding, 90 days after debonding. Method of measurement: Evaluation from cast taken from the patient on the days of measurement.;Overjet. Timepoint: Day of debonding, 30 days after debonding, 90 days after debonding. Method of measurement: Examination in the patient's mouth on the days of measurement.;Overbite. Timepoint: Day of debonding, 30 days after debonding, 90 days after debonding. Method of measurement: Examination in the patient's mouth on the days of measurement.;Bleeding after gingival probing. Timepoint: Day of debonding, 30 days after debonding, 90 days after debonding. Method of measurement: Examination in the patient's mouth on the days of measurement.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein agha Aghili

Yazd University of Medical Sciences

hosseinaghily@gmail.com+98 35 3625 5881

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026