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Effect of growth hormone in the treatment of infertility

Effect of growth hormone intrauterine injection along oral hormone replacement on refractory thin endometrium in frozen embryo transfer cycles

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210220050429N1
Enrollment
25
Registered
2021-04-13
Start date
2021-04-19
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Women infertility. Women infertility

Interventions

Intervention group: In this prospective after-before interventional study, 25 patients aged 19-45 years with a history of endometrial thickness less than 7 mm in the estrogen therapy cycle of frozen e

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
19 Years to 45 Years

Inclusion criteria

Inclusion criteria: 25 infertile women aged 19-45 years with a history of endometrial thickness less than 7 mm on the last day of endometrial preparation with estrogen in the previous cycle of embryo transfer.

Exclusion criteria

Exclusion criteria: Age over 45 years, Diabetic patients, History of cancer, Cardiovascular disease, Any disease that threatens the mother's life and prohibits pregnancy and fetal transfer, Uterus with adenomyosis and uterine fibroids, History of thrombosis, liver disease, Dyslipidemia

Design outcomes

Primary

MeasureTime frame
Chemical pregnancy. Timepoint: 2 weeks after embryo transfer. Method of measurement: Check of serum BHCG.;Clinical pregnancy. Timepoint: 4weeks after embryo transfer. Method of measurement: Seeing intra uterine gestational sac in vaginal sonography.;Ongoing pregnancy. Timepoint: 10 weeks after embryo transfer. Method of measurement: Sonography and see the heart beat of embryo.;Increase in endometrial thickness after intrauterine infusion of growth hormone. Timepoint: Measurement endometrial thickness at the beginning and at the end day of intrauterine growth hormone injection. Method of measurement: Trans sagittal vaginal sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSoghra Hosseini Aghdam

Tabriz University of Medical Sciences

dr.s.aghdam@gmail.com+98 41 3553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 11, 2026