Therapeutic effects of herbs on eczema

Evaluation of anti-inflammatory effects of ZAX.1400.EC.02 drug on skin inflammation in patients with eczema

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210218050404N3

Enrollment

110

Registered

2022-02-14

Start date

2022-03-05

Completion date

Unknown

Last updated

2022-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eczema. Allergic contact dermatitis, unspecified cause

Interventions

Intervention 1: Intervention group: ZAX.1400.EC.02 drug composition, topical and cream-based, twice-daily use for 21 days, and patients are evaluated for up to 42 days. Intervention 2: Control group:

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Diagnosis of the disease by a doctor Both sexes (male and female) Having informed and written consent to participate in the study

Exclusion criteria

Exclusion criteria: Pregnancy and lactation Food and health allergies ???? ???? ? ????? ???? ?? ?????? Disagreement of the physician directly responsible for the patient

Design outcomes

Primary

Measure	Time frame
Extent of lesion. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Determine the area in CM2.;Redness of the skin. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Swelling of the skin. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Scaling. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Itching. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Skin dryness. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: VAS checklist.;Skin irritation. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Skin scratches. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Skin scars. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Skin thickness. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Skin rash. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Recovery time. Timepoint: daily. Method of measurement: By day by checklist.	—

Measure

Time frame

Extent of lesion. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Determine the area in CM2.;Redness of the skin. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Swelling of the skin. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Scaling. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Itching. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Skin dryness. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: VAS checklist.;Skin irritation. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Skin scratches. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Skin scars. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Skin thickness. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Skin rash. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: Visual Analogue Scale checklist.;Recovery time. Timepoint: daily. Method of measurement: By day by checklist.

—

Secondary

Measure	Time frame
Quality of Life. Timepoint: In seven turns; Days zero, 7, 14, 21, 28, 35 and 42. Method of measurement: DLQI form.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmin Dakhili Ardestani

Fasa University of Medical Sciences

amindakhiliardestani@yahoo.com0715335907

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026