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Comparison of hemodynamic index and duration of effect of two drugs, bupivacaine and ropevacaine during spinal and epidural analgesia in orthopedic lower extremity surgery and umbilical cord surgery (T8 level)

Comparison of hemodynamic index and duration of effect of two drugs, bupivacaine and ropevacaine during spinal and epidural analgesia in orthopedic lower extremity surgery and umbilical cord surgery (T8 level)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210218050400N1
Enrollment
60
Registered
2021-03-04
Start date
2021-04-21
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Spinal T8 level. Condition 2: T8 level analgesic epidural.

Interventions

Intervention 1: Intervention group 1: 30 people in intervention group 1 will be injected 20 ml of rupivacaine into the epidural space once before the operation using a 3 cm multifunctional epidural ca

Sponsors

Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients referred to Imam Reza Hospital who underwent lower limb orthopedics and umbilical cord surgery without underlying disease, using a tourniquet without bleeding and operation time less than 1 hour and 45 minutes

Exclusion criteria

Exclusion criteria: People with any underlying disease, people who have a ban on spinal anesthesia (such as coagulation disorders, infection at the site of anesthesia and unwillingness to anesthetize hypovolemia

Design outcomes

Primary

MeasureTime frame
Blood pressure. Timepoint: Every 5 minutes to 30 minutes after injection and then every 15 minutes until the end of the operation. Method of measurement: Blood pressure monitor.;Blood oxygen level. Timepoint: Every 5 minutes to 30 minutes after injection and then every 15 minutes until the end of the operation. Method of measurement: Pulse oximetry.;Duration of anesthesia. Timepoint: Every 5 minutes to 30 minutes after injection and then every 15 minutes until the end of the operation. Method of measurement: Based on sensory level.;Intensity of sensory block. Timepoint: Every 5 minutes to 30 minutes after injection and then every 15 minutes until the end of the operation. Method of measurement: Based on sensory level.;The effectiveness of drugs. Timepoint: Intervals of 5 minutes for the first 30 minutes after injection. Method of measurement: Using 100 mm analog pain scores (VAPS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtiye Validad

Birjand University of Medical Sciences

Pooh199069@yahoo.com+98 915 164 0940

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026