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Evaluating the effect of beetroot extract supplementation coinciding with resistance training in rehabilitation of athletes with anterior cruciate ligament rupture

Evaluating the effect of beetroot extract supplementation coinciding with resistance training on maximum concentric peak torque and power of the quadriceps and hamstring muscles in semi-professional male athletes after anterior cruciate ligament surgery

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210217050393N2
Enrollment
46
Registered
2021-07-26
Start date
2021-06-22
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior cruciate ligament rehabilitation. Muscle wasting and atrophy, not elsewhere classified, unspecified site

Interventions

Intervention 1: Intervention group: 250 cc beetroot extract containing 40% ADI nitrate based on body weight will be given to the athlete two hours before exercise in two non-consecutive sessions. The

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Male semi-professional athletes who play in provincial teams in the fields of football, futsal, volleyball and basketball Undergoing ACL reconstructing surgery using allograft technique 90 days have passed since the ACL reconstruction surgery Adhere to the same protocol, which includes 40 sessions of physiotherapy with 60 sessions of exercise therapy, from the day of surgery to the end of 90 days for all subjects Willingness to participate in research Age between 18 and 35 years old

Exclusion criteria

Exclusion criteria: Disease including: diabetes, kidney stones, gallstones, cancer and other serious diseases Taking any medication or performing extra exercise compared to the research protocol Using oral and injectable nutritional supplements before and after the research period Consumption of any herbal medicine Allergy to beetroot Smoking Alcohol consumption History of performing any surgery on the operated limb Bilateral knee injuries Damage to other tissues and ligaments of the knee, including intra-articular fractures

Design outcomes

Primary

MeasureTime frame
Maximum concentric torque of quadriceps and hamstring at 60 degree per second. Timepoint: Baseline and 48 hours after the last exercise session (4 weeks). Method of measurement: Isokinetic device at 60 degree per second.;Maximum concentric torque of quadriceps and hamstring at 90 degree per second. Timepoint: Baseline and 48 hours after the last exercise session (4 weeks). Method of measurement: Isokinetic device at 90 degree per second.;Maximum concentric torque of quadriceps and hamstring at120 degree per second. Timepoint: Baseline and 48 hours after the last exercise session (4 weeks). Method of measurement: Isokinetic device at 120 degree per second.;Power of quadriceps and hamstring muscles at 60 degree per second. Timepoint: Baseline and 48 hours after the last exercise session (4 weeks). Method of measurement: Isokinetic device at 60 degree per second.;Power of quadriceps and hamstring muscles at 90 degree per second. Timepoint: Baseline and 48 hours after the last exercise session (4 weeks). Method of measurement: Isokinetic device at 90 degree per second.;Power of quadriceps and hamstring muscles at 120 degree per second. Timepoint: Baseline and 48 hours after the last exercise session (4 weeks). Method of measurement: Isokinetic device at 120 degree per second.

Secondary

MeasureTime frame
Body composition. Timepoint: Baseline and 48 hours after the last exercise session (4 weeks). Method of measurement: Body analyzer device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Rezvani

Mashhad University of Medical Sciences

rezvanir@mums.ac.ir+98 51 3800 2418

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026