coronary heart disease. Atherosclerotic heart disease of native coronary artery
Conditions
Interventions
Intervention 1: Intervention group 1: Three 1000 mg tablets of concentrated red beet daily (containing 22 mg of nitrate as active ingredient and other compounds including betalines, carotenoids, pheno
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age 30 to 65 years male and female with chronic coronary artery disease Willingness to participate in research
Exclusion criteria
Exclusion criteria: Body Mass Index more than 30 kg / m2 Disease (diabetes, kidney stones, gallstones, cancer and other chronic diseases) Acute heart accident in the past year Taking any medicine outside the treatment protocol Using oral and injectable nutritional supplements for at least the last 4 months (vitamins D, C, E, calcium, magnesium, potassium and multivitamin-mineral, omega 3) Consumption of any herbal medicines Allergy to red beet Pregnancy and breastfeeding Smoking and drugs Alcohol consumption Nitrate-containing drugs (such as nitroglycerin, isosorbide) The occurrence of any accident that affects a person's health Having any acute illness during the study Reluctance to continue cooperation in research Do not take more than 10% of tablets
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulse Wave Velocity. Timepoint: before and after intervention. Method of measurement: with pulse velocimetry.;Augmentation index. Timepoint: before and after intervention. Method of measurement: with pulse velocimetry.;Flow mediate dilation. Timepoint: before and after intervention. Method of measurement: with pulse velocimetry.;VO2max. Timepoint: before and after intervention. Method of measurement: CPET device.;Lipid profile. Timepoint: before and after intervention. Method of measurement: blood test.;Interleukin 6. Timepoint: before and after intervention. Method of measurement: blood test.;High sensitive-C Reactive Protein. Timepoint: before and after intervention. Method of measurement: blood test.;Intercellular-adhesion molecule (I-CAM). Timepoint: before and after intervention. Method of measurement: blood test.;Vascular cell adhesion molecule (VCAM). Timepoint: before and after intervention. Method of measurement: blood test.;Systolic blood pressure. Timepoint: before and after intervention. Method of measurement: Sphygmomanometer.;Diastolic blood pressure. Timepoint: before and after intervention. Method of measurement: Sphygmomanometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: before and after intervention. Method of measurement: digital scale.;Waist circumference. Timepoint: Before and after the intervention. Method of measurement: Non-elastic meters.;Neck circumference. Timepoint: Before and after the intervention. Method of measurement: Non-elastic meters.;Waist to hip ratio. Timepoint: Before and after the intervention. Method of measurement: Waist to hip ratio.;Body Shape Index. Timepoint: Before and after the intervention. Method of measurement: waist circumference/ body mass index 2/3* height 1/2.;Body mass index. Timepoint: Before and after the intervention. Method of measurement: weight/(height)2.;Quality of life and health. Timepoint: Before and after the intervention. Method of measurement: SF36 questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactReza Rezvani
Mashhad University of Medical Sciences
Outcome results
None listed