Dysphagia following cerebral infarction. Dysphagia following cerebral infarction
Conditions
Interventions
Intervention 1: Intervention group:Tablet Pyridostigmine 60 mg TDS before each meals for one month. Intervention 2: Control group: a Placebo tablet one before each meal (three times a day) for one mo
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with ischemic stroke revealed by CT scan or MRI 14 to 180 days before intervention and diagnosed to have post-stroke dysphagia according to MASA score(more than 177) and PSR time(more than 1.5 s) assessed by a speech pathologist.
Exclusion criteria
Exclusion criteria: Younger than 18 Hemorrhagic stroke Stroke onset before 14 days or after 180 days Head and/or neck injuries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Grade of patients dysphagia according to Mann Assessment of Swallowing Ability score sheet. Timepoint: Measuring the score of Mann Assessment of Swallowing Ability questionnaire in patients at the beginning of the study (before the intervention) and 30 days after the use of pyridostigmine. Method of measurement: Mann Assessment of Swallowing Ability questionnaire.;Pharyngeal swallowing Reflex time. Timepoint: Measurement of pharyngeal swallowing reflex time in patients at the beginning of the study (before the intervention) and 30 days after the use of pyridostigmine. Method of measurement: Assessed by Speech pathologist bedside. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyedeh Enssieh Hashemi
Iran University of Medical Sciences
Outcome results
None listed