Poisoning by methadone. Poisoning by methadone, undetermined
Conditions
Interventions
Intervention 1: Control group:This group includes people who have been exposed to methadone poisoning and have referred to Ayatollah Kashani Hospital in Shahrekord and have the inclusion criteria and
Sponsors
Shahre-kord University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All patients with opioid triad include decreased level of consciousness, myotic pupil and decreased level of blood oxygen Methadone level is positive in their urine test (U / A)
Exclusion criteria
Exclusion criteria: Patient dissatisfaction to participate in the study Use of supplements and drugs with similar effects or interventions with Naloxone and Silymarin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum level of Aspartate transaminase. Timepoint: Measurement of the variable before the intervention and 3 days after the intervention with silymarin. Method of measurement: They are measured on serum by commercial kits of Pars Azmoun company Italian BT3000 auto analyzer.;Serum level of Alanine transaminase. Timepoint: Measurement of the variable before the intervention and 3 days after the intervention with silymarin. Method of measurement: They are measured on serum by commercial kits of Pars Azmoun company Italian BT3000 auto analyze.;Serum level of Blood urea nitrogen. Timepoint: Measurement of the variable before the intervention and 3 days after the intervention with silymarin. Method of measurement: They are measured on serum by commercial kits of Pars Azmoun company Italian BT3000 auto analyze.;Serum level of Creatinine. Timepoint: Measurement of the variable before the intervention and 3 days after the intervention with silymarin. Method of measurement: They are measured on serum by commercial kits of Pars Azmoun company Italian BT3000 auto analyze.;Serum level of Uric Acid. Timepoint: Measurement of the variable before the intervention and 3 days after the intervention with silymarin. Method of measurement: They are measured on serum by commercial kits of Pars Azmoun company Italian BT3000 auto analyze.;Serum level of Lactate dehydrogenase. Timepoint: Measurement of the variable before the intervention and 3 days after the intervention with silymarin. Method of measurement: They are measured on serum by commercial kits of Pars Azmoun company Italian BT3000 auto analyze.;Serum level of Creatine phosphokinase. Timepoint: Measurement of the variable before the intervention and 3 days after the intervention with silymarin. Method of measurement: They are measured on serum by commercial kits of Pars Azmoun company Italian BT3000 auto analyze.;Serum level of Sodium. Timepoint: Measurement of the variable before the intervention and 3 days after the intervention | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactPantea Ramezan Nezhad
Shahre-kord University of Medical Sciences
Outcome results
None listed