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The effect of tDCS on the treatment of neuropathic pain in diabetics

Evaluation the effect of transcranial stimulation of the primary motor cortex (M1) in comparison with the transcranial stimulation of the primary motor cortex (M1) and the left dorsolateral prefrontal cortex (F3) on the bio-physiological and psychological status of patients with type 2 diabetes with neuropathic pain

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210214050363N1
Enrollment
30
Registered
2021-06-14
Start date
2021-06-21
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuropathic pain in diabetes. Other chronic pain

Interventions

Intervention 1: Intervention group 1: Primary motor cortical anodic tDCS group of the brain (M1)
the group receives 12 sessions, 3 days a week
each session will last 40 minutes (20 minutes left M1 stimulation and 20 minutes right M1 stimulation) in that patients will receive transcranial direct current stimulation (tDCS) for the M1 region wi
this group receives 12 sessions, 3 days a week. Therr will be 20 minutes of M1 anodic tDCS (10 minutes left M1 stimulation and 10 minutes of right M1 stimulation) and 20 minutes of F3 region anodic tD
for this group, the tDCS device, equipped with the default settings for sham stimulation, will provide real stimulation for 20 seconds, then despite remaining of the anode pad on M1 region for 20 minu

Sponsors

Payam-e-Noor University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 55 Years

Inclusion criteria

Inclusion criteria: Having at least 3 year history of diabetes Having neuropathic pain Not receiving psychological treatment since the diagnosis Having at least middle school education Being right-handed

Exclusion criteria

Exclusion criteria: Acute psychological illness Having a pacemaker or intracardiac defibrillator

Design outcomes

Primary

MeasureTime frame
Pain score on the McGill Pain Scale. Timepoint: Measurement of pain at the beginning of the study (before the intervention), immediately after the last intervention session, 30 days after the intervention. Method of measurement: the McGill Pain Scale.;HB A1c. Timepoint: Measurement of HB a1c before the study (last test in two-three months before the intervention), immediately after the last intervention session, 3 months after the intervention. Method of measurement: blood test.;Glucagon. Timepoint: Measurement of pain at the beginning of the study (before the intervention), immediately after the last intervention session, 30 days after the intervention. Method of measurement: blood test.;Insulin. Timepoint: Measurement of pain at the beginning of the study (before the intervention), immediately after the last intervention session, 30 days after the intervention. Method of measurement: blood test.;Cortisol. Timepoint: Measurement of pain at the beginning of the study (before the intervention), immediately after the last intervention session, 30 days after the intervention. Method of measurement: blood test.;Metanephrine. Timepoint: Measurement of pain at the beginning of the study (before the intervention), immediately after the last intervention session, 30 days after the intervention. Method of measurement: blood test.;Normetanephrine. Timepoint: Measurement of pain at the beginning of the study (before the intervention), immediately after the last intervention session, 30 days after the intervention. Method of measurement: blood test.;White cell count. Timepoint: Measurement of pain at the beginning of the study (before the intervention), immediately after the last intervention session, 30 days after the intervention. Method of measurement: blood test.;Red blood cell count. Timepoint: Measurement of pain at the beginning of the study (before the intervention), immediately after the last intervention session, 30 days after the intervention. Method of measurement:

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRogayeh mohammadi

PayameNoor university

rogayeh.mohammadi@gmail.com+98 41 3773 0075

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026