major abdominal surgery. personal history of major abdominal surgery
Conditions
Interventions
Intervention 1: Intervention group: Administration of 100 mg per kg of body weight of 20% magnesium sulfate solution for a total of 24 hours in equal parts per liter of isotonic saline solution prescr
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Candidates for major abdominal surgery Candidates for icu after abdominal surgery
Exclusion criteria
Exclusion criteria: heart failure renal failure hepatic failure sensitivity to magnesium sulfate poisoning to magnesium sulfate drug abuse neuromuscular disease Dissatisfaction Lack of cooperation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: every 3 hours. Method of measurement: After the necessary training to the patient, pain intensity is measured every 3 hours for 24 hours based on the unit of numerical pain rating scale.;Level of Prescription morphin. Timepoint: every 3 hours. Method of measurement: The total morphine injected in the first 24 hours of entering the ICU to reduce the severity of pain is calculated to be less than 3.;Level of serum magnesium sulfate. Timepoint: Upon arrival and after 24 hours. Method of measurement: Serum magnesium sulfate levels are measured by blood sample at the time of entry into the ICU and after 24 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: every 3 hours. Method of measurement: Sphygmomanometer.;Respiratory rate. Timepoint: every 3 hour. Method of measurement: counting respiratory rate in 1 minute.;Pulse rate. Timepoint: every 3 hours. Method of measurement: pulseoxymetery.;O2 saturation. Timepoint: every 3 hours. Method of measurement: pulseoxymetery. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactArash Peivandi Yazdi
Mashhad University of Medical Sciences
Outcome results
None listed