Comparison of the Manual Therapy and Muscle Contraction in the treatment of Patients with Knee Arthrosis

Comparison of the Non-thrust Manipulation VS. Muscle Energy Techniques in the Management of Patients with Knee Osteoarthritis: A Randomized Clinical Trial.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210214050356N2

Enrollment

Registered

2021-10-17

Start date

2021-10-23

Completion date

Unknown

Last updated

2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis. Unilateral primary osteoarthritis of knee

Interventions

Intervention 1: Intervention group: Group A: will receive non-thrust manipulation supplemented with supervised exercises and TENS program at the clinic (three times a week), consisting of 10 sessions

Eligibility

Sex/Gender

All

Age

35 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients with knee OA (diagnosed already) Age 35 -65 years Grade 2 Kellgren-Lawrence radiographic confirmed OA Unilateral or bilateral knee OA. Chronic stages of knee pain. Patients who scored 30mm out of 100mm knee pain or greater on the VAS with activity intervention at baseline. Those who consented were able to ambulate at least 30 meters on an even surface with or without a walking device and were able to perform physical exercises with minimal support. WOMAC score above 10. Knee extension lack 10 degrees or more.

Exclusion criteria

Exclusion criteria: Acute pain and inflammation. Recent fractures. Patients having other major musculoskeletal problems and having with red flag signs and patients with recent history of knee trauma.• Prolonged immobilization. Uncontrolled hypertension. Severe cardiopulmonary disease. Mentally challenged. Severe osteoporosis. Rheumatoid arthritis. Neurological disorders affecting lower limb. Individuals with impaired function such as stroke, neoplastic disorder and hip or knee arthroplasty. Gout or Psedo-gout. Hyper/ hypo-thyroidism.

Design outcomes

Primary

Measure	Time frame
Pain Intensity (at rest). Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: Visual Analogue Scale.;Pain Intensity (during activities). Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: Visual Analogue Scale.;Knee Extension Lack. Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: Passive Knee Extension Test by using Goniometer.;Functional impairment. Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).	—

Measure

Time frame

Pain Intensity (at rest). Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: Visual Analogue Scale.;Pain Intensity (during activities). Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: Visual Analogue Scale.;Knee Extension Lack. Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: Passive Knee Extension Test by using Goniometer.;Functional impairment. Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).

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Secondary

Measure	Time frame
Distance Covered. Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: Six Minutes Walking Test (6MWT).;Chair Stand Repetition. Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: 30 Seconds Chair Stand Test (30CST).;Knee Mal-alignment. Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: Tibio-Femoral Angle (TFA) by using Goniometer.	—

Measure

Time frame

Distance Covered. Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: Six Minutes Walking Test (6MWT).;Chair Stand Repetition. Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: 30 Seconds Chair Stand Test (30CST).;Knee Mal-alignment. Timepoint: Before intervention- After the 10th intervention session (last session). Method of measurement: Tibio-Femoral Angle (TFA) by using Goniometer.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Fereydounnia

Tehran University of Medical Sciences

S-fereydounnia@sina.tums.ac.ir+98 21 7752 8468

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026