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Evaluating the premedication effects of Fentanyl and Ketamine on perioperative hemodynamic stability and postoperative pain in patients undergoing general anesthesia

Comparing the premedication effects of Fentanyl and Ketamine on perioperative hemodynamic stability and postoperative pain in patients undergoing general anesthesia using laryngeal mask for cataract surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20210214050355N1
Enrollment
98
Registered
2021-05-25
Start date
2021-04-04
Completion date
Unknown
Last updated
2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract. Age-related cataract

Interventions

Intervention 1: Intervention group 1: In this group, patients have prescribed 0.3 mg/kg ketamine as a premedication. After 3 minutes, induction of anesthesia with propofol at a dose of 1.5 mg/kg intra

Sponsors

Sanandaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients with cataracts Age 40 to 70 years Being at level 1 and 2 of the ASA system Consent to participate in research

Exclusion criteria

Exclusion criteria: Uncontrolled Cardiovascular disease Opioids abuse during the weak before operation Patients who are taking corticosteroids Ear disorders and Vertigo Uncontrolled Diabetes Mellitus Uncontrolled Hypertension Acute or chronic Pulmonary diseases Obesity (BMI>30) Probable Schizophrenia; Schizophrenia and in treatment Schizophrenia Brain mass; Hydrocephalus; Raised ICP Porphyria Thyroid malfunction Patients whose operation lasts more than an hour

Design outcomes

Primary

MeasureTime frame
Mean Arterial Pressure. Timepoint: Induction time of venous anesthesia, After induction and before placement of laryngeal mask, Immediately after laryngeal mask placement, Ten minutes after induction of anesthesia,20 minutes after induction of anesthesia, Recovery Delivery Time, Recovery Discharge Time. Method of measurement: Barometer of medical monitoring device.;Harte Rate. Timepoint: Induction time of venous anesthesia, After induction and before placement of laryngeal mask, Immediately after laryngeal mask placement, Ten minutes after induction of anesthesia,20 minutes after induction of anesthesia, Recovery Delivery Time, Recovery Discharge Time. Method of measurement: Medical monitoring device.;Pain. Timepoint: 30 and 60 minutes after the end of anesthesia. Method of measurement: Visual analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehran Rami

Sanandaj University of Medical Sciences

Mehran.Rami@gmail.com+98 87 3361 1233

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026