Idiopathic overactive bladder. disease of the genitourinary system
Conditions
Interventions
Intervention 1: Control group: As traditional method , spinal or general anesthesia is used. Patients will be hospitalized at least for one day after procedure . In each injection, 0.5 cc Botox are ap
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Idiopathic overactive bladders resistant to anticholinergic drugs taking at least four weeks. Anticholinergic medication intolerance due to side effects Anticholinergic contraindications
Exclusion criteria
Exclusion criteria: Neurogenic bladder due to CVA , Multiple sclerosis, Spinal cord injury , head trauma , Parkinson , disc herniations . Severe bladder outlet obstruction Recurrent UTI Urinary tract anomalies Previous bladder surgery History of pelvic radiation History of pelvic malignancies Pregnancy Age < 18 years old Male
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of urodynamic results of Minimistic intra-detrusor botulinum injection and traditional technique during bladder storage phase in patients with idiopathic over active bladder. Timepoint: Urodynamic study before Botulinum injection and after 4-6 weeks post injection. Method of measurement: Urodynamic study. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessing the mean of maximum detrusor pressure in filling phase in traditional method. Timepoint: Before intervention and 4-6 weeks after Botox injection. Method of measurement: Urodynamic study.;Assessing the mean of maximum detrusor pressure in filling phase in Minimistic method. Timepoint: Before intervention and 4-6 weeks after Botox injection. Method of measurement: Urodynamic study.;Comparison of the mean of maximum detrusor pressure in filling phase in both Minimistic and traditional methods. Timepoint: Before intervention and 4-6 weeks after Botox injection. Method of measurement: Urodynamic study.;Assessing the mean of each detrusor over-activity duration in traditional method. Timepoint: Before intervention and 4-6 weeks after Botox injection. Method of measurement: Urodynamic study.;Assessing the mean of each detrusor over-activity duration in Minimistic method. Timepoint: Before intervention and 4-6 weeks after Botox injection. Method of measurement: Urodynamic study.;Comparison of the mean of each detrusor over-activity duration in both Minimistic and traditional methods. Timepoint: Before intervention and 4-6 weeks after Botox injection. Method of measurement: Urodynamic study.;Assessing the mean of bladder capacity in beginning of each detrusor over-activity in traditional method. Timepoint: Before intervention and 4-6 weeks after Botox injection. Method of measurement: Urodynamic study.;Assessing the mean of bladder capacity in beginning of each detrusor over-activity in Minimistic method. Timepoint: Before intervention and 4-6 weeks after Botox injection. Method of measurement: Urodynamic study.;Comparison of the mean of bladder capacity in beginning of each detrusor over-activity in both traditional and Minimistic methods. Timepoint: Before intervention and 4-6 weeks after Botox injection. Method of measurement: Urodynamic study.;Assessing the mean of functional bladder capacity in traditional method. Timepoint: Before intervention an | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Emami
Iran University of Medical Sciences
Outcome results
None listed