The effect of antibiotic lock on catheter persistence in hemodialysis patients

The evaluation of efficacy of antibiotic lock accompanied by systemic antibiotic therapy in permanent haemodialysis by probability of catheter infection on the rate of infection of the catheter

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20210214050352N1

Enrollment

Registered

2021-08-04

Start date

2021-03-05

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Permi-cath infection. Infection due to central venous catheter

Interventions

Intervention 1: Intervention group: 30 patients for whom standard systemic antibiotic therapy of vancomycin 7.5mg / kg as stat and ceftazidime 2 gr as stat after each dialysis will be performed by pe

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: End stage renal disease patients whose hemodialysis is performed using permi-cath and have a fever and have been hospitalized with a possible diagnosis of an infection catheter

Exclusion criteria

Exclusion criteria: Catheter Tunnel Infection Simultaneous infection of non-catheter origin HIV positive patients Intravenous drug users Immunodeficiency Severe sepsis

Design outcomes

Secondary

Measure	Time frame
Duration of hospitalization. Timepoint: When discharged from the hospital. Method of measurement: Based on hospitalization file.	—

Primary

Measure	Time frame
Fever. Timepoint: Every 8 hours. Method of measurement: Mercury Therommeter.;Leukocytosis. Timepoint: Daily. Method of measurement: Blood cell counter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmad Saebian

Arak University of Medical Sciences

Ahmad.saebian@yahoo.com+98 86 3417 3645

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026