Migraine. Chronic migraine without aura, intractable, with status migrainosus
Conditions
Interventions
Intervention 1: Intervention group: Intervention group: The patient undergoes RIPC protocol 6 days a week. sphygmomanometer will be attached to the patient's arm and will be remained under the pressur
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Patient have at least 5 headache attacks lasting 4–72 hours (without treatment or unsuccessful treatment) Age range from 18 to 50 years The onset of migraines before menopause The ability of patients to distinguish migraine headaches from other conditions The patient's ability to fill out questionnaire Both male and female gender Informed consent
Exclusion criteria
Exclusion criteria: Underlying diseases, history of chronic diseases or kidney, liver, cardiovascular, renal, pulmonary diseases, any malignancy, autoimmunity, diabetes mellitus Convulsions Menopause Head and neck trauma Asthenic damage Mental disorders and major depression according to DSM4 Botox injection in the last 6 months Pregnancy and lactation Non-migraine headaches such as tension headaches that occur more than 12 times a month and cervicogenic Drug and alcohol dependence during the 1 year prior to the study Migraine with aura History of off pump surgery Severe hypertension higher than 160/90 mm / hg Rheumatism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glutamate. Timepoint: Days 0 and 60. Method of measurement: Magnetic resonance spectroscopy (MRS) test.;N-acetyl aspartate. Timepoint: Days 0 and 60. Method of measurement: MRS test.;Choline. Timepoint: Days 0 and 60. Method of measurement: MRS test.;Creatine. Timepoint: Days 0 and 60. Method of measurement: MRS test.;Myoinositol. Timepoint: Days 0 and 60. Method of measurement: MRS test.;GABA. Timepoint: Days 0 and 60. Method of measurement: MRS test.;Glutamate/Creatine. Timepoint: Days 0 and 60. Method of measurement: Math.;NAA/Cr. Timepoint: Days 0and 60. Method of measurement: Math.;Choline/Cr. Timepoint: Days 0 and 60. Method of measurement: Math.;Myoinisitol/Cr. Timepoint: Days 0and 60. Method of measurement: Math.;Absolute frequency bands. Timepoint: Days 0 and 60. Method of measurement: Qeeg.;Relative frequency bands. Timepoint: days 0and 60. Method of measurement: Qeeg.;Coherence. Timepoint: Days 0 and 60. Method of measurement: Qeeg analyze. | — |
Secondary
| Measure | Time frame |
|---|---|
| Migraine-induced disability. Timepoint: Days 0 and 90. Method of measurement: According to the MIDAS index. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmaneh Mohammadi Roushandeh
Rasht University of Medical Sciences
Outcome results
None listed