Migraine. Chronic migraine without aura, Intractable, With status migraineurs
Conditions
Interventions
Intervention 1: Intervention group: The patient undergoes RIPC protocol 6 days/ week. sphygmomanometer will be fastened to the patient's arm and will be remained under the pressure of 200 mmHg for 5 m
Sponsors
Rasht University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Patient have at least 5 headache attacks lasting 4–72 hours (without treatment or unsuccessful treatment) Age range 18 to 50 years Both male and female Gender The onset of migraines before menopause Ability of Patient to distinguish migraine headaches from other conditions Ability to fill out questionnaire Signed informed consent
Exclusion criteria
Exclusion criteria: Presence of underlying diseases, history of chronic diseases or kidney, liver, cardiovascular, renal, pulmonary diseases, any malignancy, autoimmunity diseases, diabetes mellitus Convulsions Menopause Head and neck trauma Existence of asthenic damage Mental disorders and major depression according to DSM4 Botox injection in the last 6 months Pregnancy and lactation Severe hypertension greater than 160/90 mm / hg Non-migraine headaches such as tension headaches that occur more than 12 times a month and cervicogenic Drug and alcohol dependency during one year prior to the study Rheumatism Migraine with aura History of off - pump surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Headache intensity. Timepoint: Each time after the migraine attack (day 0 -60). Method of measurement: According to the VAS index.;Migraine-induced disability. Timepoint: Days 0 and 90. Method of measurement: According to the MIDAS index.;Time of migraine start. Timepoint: At the admission. Method of measurement: Asking from patients.;Blood CGRP level. Timepoint: Days 0and 60. Method of measurement: ELISA kit.;Blood lactate level. Timepoint: ?Days 0 and 60. Method of measurement: Blood test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Migraine-induced disability. Timepoint: Days 0 and 90. Method of measurement: According to the MIDAS index. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmaneh Mohammadi Roushandeh
Rasht University of Medical Sciences
Outcome results
None listed