Multiple sclerosis. Multiple sclerosis
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Definitive diagnosis of multiple sclerosis by a neurologist Radiographic findings of magnetic resonance imaging ( MRI ) consistent with the clinical diagnosis of multiple sclerosis No other concomitant inflammatory disease Bad cholesterol levels (low-density lipoprotein) less than 130 mg / dL No pregnancy and lactation Do not take medications other than standard treatments for multiple sclerosis that alter the levels of the factors under consideration. Do not use any combination with antioxidant effects in the past month.
Exclusion criteria
Exclusion criteria: Existing evidence based on increased patient disability Consumption of any combination or drug with antioxidant effects except prescription drugs Existence of any cognitive or behavioral disorders that lead to the patient not cooperating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sirtuin1 gene expression. Timepoint: Before the intervention and 3 months after the start of the intervention. Method of measurement: Laboratory. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expanded Disability Status Scale (EDSS ) score. Timepoint: Before the intervention and 3 months after the start of the intervention. Method of measurement: Expanded Disability Status Scale (EDSS) questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Hamedan University of Medical Sciences